GRBs as Probes of the IGM

Gamma-ray Bursts (GRBs) are the most powerful explosions known, capable of outshining the rest of gamma-ray sky during their short-lived prompt emission. Their cosmological nature makes them the best tool to explore the final stages in the lives of very massive stars up to the highest redshifts. Furthermore, studying the emission from their low-energy counterparts (optical and infrared) via rapid spectroscopy, we have been able to pin down the exact location of the most distant galaxies as well as placing stringent constraints on their host galaxies and intervening systems at low and high-redshift (e.g. metallicity and neutral hydrogen fraction). In fact, each GRB spectrum contains absorption features imprinted by metals in the host interstellar medium (ISM) as well as the intervening intergalactic medium (IGM) along the line of sight. In this chapter we summarize the progress made using a large dataset of GRB spectra in understanding the nature of both these absorbers and how GRBs can be used to study the early Universe, in particular to measure the neutral hydrogen fraction and the escape fraction of UV photons before and during the epoch of re-ionization.Comment: 18 pages; 5 Figures. Accepted for publication in Space Science Review

Neighbor cache prefetching for multimedia image and video processing

Cache performance is strongly influenced by the type of locality embodied in programs. In particular, multimedia programs handling images and videos are characterized by a bidimensional spatial locality, which is not adequately exploited by standard caches. In this paper we propose novel cache prefetching techniques for image data, called neighbor prefetching, able to improve exploitation of bidimensional spatial locality. A performance comparison is provided against other assessed prefetching techniques on a multimedia workload (with MPEG-2 and MPEG-4 decoding, image processing, and visual object segmentation), including a detailed evaluation of both the miss rate and the memory access time. Results prove that neighbor prefetching achieves a significant reduction in the time due to delayed memory cycles (more than 97% on MPEG-4 with respect to 75% of the second performing technique). This reduction leads to a substantial speedup on the overall memory access time (up to 140% for MPEG-4). Performance has been measured with the PRIMA trace-driven simulator, specifically devised to support cache prefetching

Improving data prefetching efficacy in multimedia applications

The workload of multimedia applications has a strong impact on cache memory performance, since the locality of memory references embedded in multimedia programs differs from that of traditional programs. In many cases, standard cache memory organization achieves poorer performance when used for multimedia. A widely-explored approach to improve cache performance is hardware prefetching, which allows the pre-loading of data in the cache before they are referenced. However, existing hardware prefetching approaches are unable to exploit the potential improvement in performance, since they are not tailored to multimedia locality. In this paper we propose novel effective approaches to hardware prefetching to be used in image processing programs for multimedia. Experimental results are reported for a suite of multimedia image processing programs including MPEG-2 decoding and encoding, convolution, thresholding, and edge chain coding

Bifidobacteria and lactobacilli in the gut microbiome of children with non-alcoholic fatty liver disease: which strains act as health players?

Introduction: Non-alcoholic fatty liver disease (NAFLD), considered the leading cause of chronic liver disease in children, can often progress from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH). It is clear that obesity is one of the main risk factors involved in NAFLD pathogenesis, even if specific mechanisms have yet to be elucidated. We investigated the distribution of intestinal bifidobacteria and lactobacilli in the stools of four groups of children: obese, obese with NAFL, obese with NASH, and healthy, age-matched controls (CTRLs). Material and methods: Sixty-one obese, NAFL and NASH children and 54 CTRLs were enrolled in the study. Anthropometric and metabolic parameters were measured for all subjects. All children with suspected NASH underwent liver biopsy. Bifidobacteria and lactobacilli were analysed in children’s faecal samples, during a broader, 16S rRNA-based pyrosequencing analysis of the gut microbiome. Results: Three Bifidobacterium spp. (Bifidobacterium longum, Bifidobacterium bifidum, and Bifidobacterium adolescentis) and five Lactobacillus spp. (L. zeae, L. vaginalis, L. brevis, L. ruminis, and L. mucosae) frequently recurred in metagenomic analyses. Lactobacillus spp. increased in NAFL, NASH, or obese children compared to CTRLs. Particularly, L. mucosae was significantly higher in obese (p = 0.02426), NAFLD (p = 0.01313) and NASH (p = 0.01079) than in CTRLs. In contrast, Bifidobacterium spp. were more abundant in CTRLs, suggesting a protective and beneficial role of these microorganisms against the aforementioned diseases. Conclusions: Bifidobacteria seem to have a protective role against the development of NAFLD and obesity, highlighting their possible use in developing novel, targeted and effective probiotics

Distortion of the Stoner-Wohlfarth astroid by a spin-polarized current

The Stoner-Wohlfarth astroid is a fundamental object in magnetism. It separates regions of the magnetic field space with two stable magnetization equilibria from those with only one stable equilibrium and it characterizes the magnetization reversal of nano-magnets induced by applied magnetic fields. On the other hand, it was recently demonstrated that transfer of spin angular momentum from a spin-polarized current provides an alternative way of switching the magnetization. Here, we examine the astroid of a nano-magnet with uniaxial magnetic anisotropy under the combined influence of applied fields and spin-transfer torques. We find that spin-transfer is most efficient at modifying the astroid when the external field is applied along the easy-axis of magnetization. On departing from this situation, a threshold current appears below which spin-transfer becomes ineffective yielding a current-induced dip in the astroid along the easy-axis direction. An extension of the Stoner-Wohlfarth model is outlined which accounts for this phenomenon.Comment: 8 pages, 6 figure

Performance analysis of MPEG-4 decoder and encoder

© 2002 Croatian Soc. Electronics in Marine-ELMAR. A performance analysis of MPEG-4 encoder and decoder programs on a standard personal computer is presented. The paper first describes the MPEG-4 computational load and discusses related works, then outlines the performance analysis. Experimental results show that while the decoder program can be easily executed in real time, the encoder requires execution times in the order of seconds per frame which call for substantial optimisation to satisfy real-time constraints